Genetic characterization of H1N1 swine influenza A viruses isolated in eastern China
Identifieur interne : 001177 ( Main/Exploration ); précédent : 001176; suivant : 001178Genetic characterization of H1N1 swine influenza A viruses isolated in eastern China
Auteurs : X. Qi [République populaire de Chine] ; B. Pang [République populaire de Chine] ; C. P. Lu [République populaire de Chine]Source :
- Virus Genes [ 0920-8569 ] ; 2009-10-01.
Descripteurs français
- Wicri :
- topic : Porcin.
English descriptors
- KwdEn :
Abstract
Abstract: Three influenza H1N1 viruses were isolated in 2005 from pigs with respiratory disease on a farm in eastern China. The three isolates were characterized to determine their probable origin. Each of the eight genes of the isolates was most closely related to the corresponding gene from the classical swine H1N1 virus. Also, phylogenetic analysis further confirmed that each of the eight genes of the isolates was closely related to the classical swine H1N1 viruses, especially those isolated in China. The HA1 proteins of the three isolates were identical to that of A/Swine/Guangdong/1/01, a virus isolated in 2001 in China, even though three nucleotide differences were observed. These results further support the concept that swine can serve as a reservoir of genetically stable influenza viruses.
Url:
DOI: 10.1007/s11262-009-0375-9
Affiliations:
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The three isolates were characterized to determine their probable origin. Each of the eight genes of the isolates was most closely related to the corresponding gene from the classical swine H1N1 virus. Also, phylogenetic analysis further confirmed that each of the eight genes of the isolates was closely related to the classical swine H1N1 viruses, especially those isolated in China. The HA1 proteins of the three isolates were identical to that of A/Swine/Guangdong/1/01, a virus isolated in 2001 in China, even though three nucleotide differences were observed. These results further support the concept that swine can serve as a reservoir of genetically stable influenza viruses.</div></front></TEI><affiliations><list><country><li>République populaire de Chine</li></country></list><tree><country name="République populaire de Chine"><noRegion><name sortKey="Qi, X" sort="Qi, X" uniqKey="Qi X" first="X." last="Qi">X. 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